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The hydroxamate of valproic acid, a compound produced by oximation of urine from patients under valproic therapy
Author(s) -
Libert R.,
Van Hoof F.,
Schanck A.,
Hoffmann E.
Publication year - 1986
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200131104
Subject(s) - valproic acid , urine , chemistry , mass spectrometry , chromatography , gas chromatography–mass spectrometry , nuclear magnetic resonance spectroscopy , organic chemistry , biochemistry , medicine , epilepsy , psychiatry
A previously unreported substance, detected by gas chromatography after oximation of urine from patients receiving valproic acid, was isolated and analysed by mass spectrometry and nuclear magnetic resonance spectroscopy. It was identified as the hydroxamate of valproic acid.