Premium
Quantitative analysis of parathion and parathion‐methyl by combined capillary column gas chromatography negative ion chemical ionization mass spectrometry
Author(s) -
Nielsen Peter G.
Publication year - 1985
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200121204
Subject(s) - chemistry , parathion , chemical ionization , mass spectrometry , parathion methyl , chromatography , selected ion monitoring , quantitative analysis (chemistry) , gas chromatography , analytical chemistry (journal) , calibration curve , ionization , detection limit , ion , gas chromatography–mass spectrometry , pesticide , organic chemistry , agronomy , biology
Deuterium‐labelled parathion and parathion‐methyl were prepared and used as internal standards in an analytical procedure for precise determinations of parathion and parathion‐methyl in complex matrices. The use of negative chemical ionization mass spectrometry in the selected ion monitoring mode gave an extremely high sensitivity and selectivity for these compounds. Calibration curves showed linearity with a correlation of 99.9% in the investigated region (0.5–500 pg) and detection limits could generally be expanded to the ppt (ng/kg) level. The procedure was applied for quantitative determination of the parathions in a marine sediment near a chemical deposit.