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Rapid, sensitive and specific determination of oxytetracycline residues in bovine milk and meat by CAD MIKES analysis at the 1 ppb level
Author(s) -
Traldi P.,
Daolio S.,
Pelli B.,
Facino R. Maffei,
Carini M.
Publication year - 1985
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200120908
Subject(s) - oxytetracycline , chemistry , chromatography , mass spectrometry , tandem mass spectrometry , bovine milk , biochemistry , antibiotics
A rapid and sensitive method for the selective detection and quantification of oxytetracycline residues at the ppb level in crude extracts of bovine milk and meat is described. The technique employed is a tandem mass spectrometric method: CAD MIKE spectrometry (collisionally activated decomposition mass‐analysed ion kinetic energy spectrometry). Quantification is performed by single ion monitoring of CAD species of oxytetracycline and of its internal standard.