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Surface effects in FAB mapping of proteins and peptides
Author(s) -
Clench Malcolm R.,
Garner George V.,
Gordon Derek B.,
Barber Michael
Publication year - 1985
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200120708
Subject(s) - chemistry , computational biology , biology
A FAB mapping study of glucagon is described. The absence of important structural information led to a further investigation of the phenomenon. It is suggested that the presence of surface active components in mixtures of peptides can seriously affect the results. It may, in the case of unknown structures, lead to incorrect assignments.