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Liquid chromatography/mass spectrometry of the thermally labile herbicides, chlorsulfuron and sulfometuron methyl
Author(s) -
Shalaby Lamaat M.
Publication year - 1985
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200120604
Subject(s) - thermospray , chemistry , chromatography , mass spectrometry , mass spectrum , fragmentation (computing) , protonation , liquid chromatography–mass spectrometry , polyatomic ion , analytical chemistry (journal) , ion , selected reaction monitoring , tandem mass spectrometry , organic chemistry , computer science , operating system
An on‐line liquid chromatographic/mass spectrometric technique with direct liquid introduction (DLI) was investigated for the analysis of chlorsulfuron, the active ingredient of Glean® herbicide and sulfometuron methyl, the active ingredient of Oust® herbicide. These compounds are thermally labile and cannot be analysed by gas chromatography. Our work reported here demonstrates that with DLI‐liquid chromatography/mass spectrometry (LC/MS) we can eliminate thermal decomposition and obtain a mass spectrum with complete fragmentation pattern and abundant protonated molecular ion. The amount of fragmentation and abundance of the protonated molecular ion can be changed by varying the source pressure or temperature. This effect is valuable for identification and quantification purposes. In addition, the study includes a comparison of chlorsulfuron spectra obtained by both DLI‐LC/MS and commercial thermospray LC/MS interface.