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Metabolite identification of missile fule JP‐10 by gas chromatography mass spectrometry
Author(s) -
Yu Kyung O.,
Inman Roger C.,
Olson Carl T.,
Serve M. Paul
Publication year - 1985
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200120508
Subject(s) - metabolite , mass spectrometry , chromatography , gas chromatography , gas chromatography–mass spectrometry , chemistry , kidney , missile , urinary system , pharmacology , medicine , biochemistry , engineering , aerospace engineering
The identification of the metabolites of the Air Force missile fuel JP‐10 was accomplished. 5‐Hydroxy‐JP‐10 was identified as the urinary metabolite of rats, mice and hamsters exposed to JP‐10. 5‐Keto‐JP‐10 was a major metabolite found in kidney extracts of male rats exposed to JP‐10 but not found in kidney extracts from female rats or from other species. Sex‐related differences in the formation of 5‐keto‐JP‐10 in rats were studied.