Premium
Desorption Ionization Mass Spectrometry of Synthetic Porphyrins
Author(s) -
Kurlansik Leon,
Williams Taffy J.,
Strong John M.,
Anderson Lawrence W.,
Campana Joseph E.
Publication year - 1984
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200110908
Subject(s) - fast atom bombardment , chemistry , mass spectrometry , mass spectrum , desorption , ionization , fragmentation (computing) , electron ionization , chemical ionization , field desorption , ion , adduct , polyatomic ion , analytical chemistry (journal) , molecule , soft laser desorption , matrix assisted laser desorption/ionization , chromatography , organic chemistry , adsorption , computer science , operating system
Abstract The desorption ionization mass spectra are reported for two classes of synthetic porphyrins—‘tailed’ derivatives of deuteroporphyrin IX and meso ‐substituted derivatized tetraphenylporphines. The mass spectra were obtained by three desorption ionization techniques—fast atom bombardment (FAB), desorption chemical ionization (DCI) and ‘in‐beam’ or desorption electron ionization (DEI). The emphasis of this study is to determine the usefulness of the three desorption ionization methods for the molecular weight and side‐chain structure determinations of synthetic porphyrins. The molecular parent ions and the major fragmentation pathways are discussed in detail. The DEI method yielded the fewest mass spectra showing molecular parent ions from the compounds studied, whereas FAB gave the most. The major fragmentation pathways were compound dependent and similar for all three ionization methods; generally, those cleavages α and β to carbonyl groups predominated. The FAB spectra showed strong molecular adduct ions in several spectra that could be attributed to an in situ coordination of iron‐containing porphyrins with the thio‐containing liquid matrix molecules.