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Electron impact mass spectrometry of some amino derivatives of 1,4‐benzodiazepines
Author(s) -
Gioia B.,
Arlandini E.,
Giacconi P.,
Rossi E.,
Stradi R.
Publication year - 1984
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200110809
Subject(s) - mass spectrum , fragmentation (computing) , electron ionization , chemistry , mass spectrometry , deuterium , metastability , ion , high resolution , benzodiazepine , mass , analytical chemistry (journal) , organic chemistry , chromatography , physics , atomic physics , biochemistry , remote sensing , receptor , computer science , ionization , geology , operating system
The electron impact mass spectra of some mono‐ and diamino derivatives of 5‐phenyl‐1,4‐benzodiazepines have been determined, and their fragmentation pattern elucidated with the aid of deuterium‐labelled derivatives, high resolution mass measurements and metastable analysis. The most significant ions are derived from the loss of the amino residues, and from the contraction of the seven‐membered benzodiazepine system to give smaller rings.