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Quantitative determination of nitroglycerol in human plasma by gas chromatography negative ion mass spectrometry using 15 N labelled nitroglycerol as internal standard
Author(s) -
Gaudry D.,
Gerardin A.,
Briand C.,
Wantiez D.
Publication year - 1984
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200110605
Subject(s) - chromatography , mass spectrometry , chemistry , plasma , ion , coefficient of variation , ionization , analytical chemistry (journal) , gas chromatography , physics , organic chemistry , quantum mechanics
Negative ionization resulted in the simplification of a previously published method. The new method permits the determination of 0.25 nmol l −1 nitroglycerol in plasma with a coefficient of variation of 9.1%.
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