Mass spectrometric identification of abnormal aromatic compounds in the urine of a child with Reye's like syndrome | Zendy

Rocchiccioli F. | Zendy; Cartier P. H. | Zendy; Bougnères P. F. | Zendy

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Mass spectrometric identification of abnormal aromatic compounds in the urine of a child with Reye's like syndrome

Author(s) -

Rocchiccioli F.,

Cartier P. H.,

Bougnères P. F.

Publication year - 1984

Publication title -

biomedical mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 121

eISSN - 1096-9888

pISSN - 0306-042X

DOI - 10.1002/bms.1200110307

Subject(s) - reye syndrome , urine , chemistry , gas chromatography–mass spectrometry , reye's syndrome , chromatography , organic chemistry , mass spectrometry , biochemistry , medicine

The urine of a young child with hypoglycemia and a Reye's like syndrome contained an excess of unusual aromatic products with a three carbon chain, phenylpropionylglycine and 3‐ and 4‐(hydroxyphenyl)propionic and 3‐(3‐methoxy‐4‐hydroxyphenyl)propionic acids, as well as of organic acids usually found in fatty acid β‐oxidation defects: the mono‐ and dicarboxylic acids derived from the respective (ω – 1) and ω‐oxidation of C 6 to C 10 fatty acids.

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