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Analysis of steroid and vitamin D glucuronides and sulfates by fast atom bombardment mass spectrometry
Author(s) -
Jardine Ian,
Scanlan Gale F.,
Mattox Ver R.,
Kumar Rajiv
Publication year - 1984
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200110103
Subject(s) - fast atom bombardment , glucuronide , chemistry , fragmentation (computing) , steroid , mass spectrometry , conjugate , sulfate , chromatography , organic chemistry , biochemistry , metabolism , biology , hormone , ecology , mathematical analysis , mathematics
The direct analysis of underivatized steroid and vitamin D glucuronide and sulfate conjugates by positive and negative ion fast atom bombardment mass spectrometry has been demonstrated. The technique allows unambiguous molecular weight determination of these conjugates and provides useful fragmentation information in many cases. Analysis of low microgram amounts of such conjugates purified from biological sources has been carried out.