The measurement of clonidine in human plasma and urine by combined gas chromatography mass spectrometry with ammonia chemical ionization | Zendy

Murray S. | Zendy; Waddell K. A. | Zendy; Davies D. S. | Zendy

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The measurement of clonidine in human plasma and urine by combined gas chromatography mass spectrometry with ammonia chemical ionization

Author(s) -

Murray S.,

Waddell K. A.,

Davies D. S.

Publication year - 1981

Publication title -

biomedical mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 121

eISSN - 1096-9888

pISSN - 0306-042X

DOI - 10.1002/bms.1200081007

Subject(s) - chemistry , chemical ionization , reagent , mass spectrometry , chromatography , clonidine , gas chromatography , ammonia , gas chromatography–mass spectrometry , urine , ionization , mass spectrum , atmospheric pressure chemical ionization , analytical chemistry (journal) , ion , organic chemistry , biochemistry , medicine , endocrinology

The dimethyl derivatives of clonidine and [ 2 H 4 ]clonidine give good chemical ionization mass spectra when ammonia is used as reagent gas. A gas chromatographic mass spectrometric selected ion monitoring assay for the estimation of clonidine in plasma and urine using ammonia chemical ionization is described.

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