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The mass spectral behaviour of bruceolides
Author(s) -
Baldwin Michael A.,
Carter David M.,
Darwish Fikria A.,
Phillipson J. David
Publication year - 1981
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200080809
Subject(s) - mass spectrometry , electron ionization , chemistry , field desorption , characterization (materials science) , kinetic energy , metastability , ion , analytical chemistry (journal) , mass spectrum , thermal ionization mass spectrometry , ionization , computational chemistry , chromatography , materials science , organic chemistry , nanotechnology , physics , quantum mechanics
A series of bruceolides isolated from Brucea javanica has been studied by electron impact, chemical ionization and field desorption mass spectrometry, and by metastable ion techniques, including mass analysed ion kinetic energy spectrometry. The spectral data obtained for one of these compounds, bruceine A, are discussed in relation to the molecular structure and are taken as an example for the bruceolide series. The bruceolides occur in plants as mixtures of closely related compounds and some of them have potent anti‐cancer activity. It is demonstrated that mass spectrometry provides a valuable tool for the identification and characterization of these compounds.