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Capillary column gas chromatographic mass spectrometric analysis of anabolic steroid residues using splitless injections made at elevated temperatures
Author(s) -
Houghton E.,
Teale P.
Publication year - 1981
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200080808
Subject(s) - chemistry , chromatography , mass spectrometry , gas chromatography , capillary action , dodecane , tetradecane , gas chromatography–mass spectrometry , anabolic steroid , urine , boiling , anabolism , nandrolone , vaporization , solvent , organic chemistry , biochemistry , materials science , composite material
The use of capillary column gas chromatography mass spectrometry has been investigated for the detection of the presence of estrane‐3,17α‐diol in horse urine extracts; the detection of this diol confirms the administration of anabolic steroids based upon 19‐nortestosterone. To reduce analysis time, but yet maintain a solvent effect in the splitless injection mode, injections have been made at elevated temperatures (190–220°C) using high boiling solvents (dodecane b.p. 214°C and tetradecane b.p. 252°C).