A new metabolite of propachlor isolated from germfree rat excreta | Zendy

Feil V. J. | Zendy; Bakke J. E. | Zendy; Larsen G. L. | Zendy; Gustafsson B. E. | Zendy

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A new metabolite of propachlor isolated from germfree rat excreta

Author(s) -

Feil V. J.,

Bakke J. E.,

Larsen G. L.,

Gustafsson B. E.

Publication year - 1981

Publication title -

biomedical mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 121

eISSN - 1096-9888

pISSN - 0306-042X

DOI - 10.1002/bms.1200080102

Subject(s) - metabolite , sulfoxide , chemistry , artifact (error) , mass spectrometry , chromatography , cysteine , biochemistry , organic chemistry , biology , enzyme , neuroscience

2‐[ S ‐( N ‐Acetyl)cysteine]‐isopropylacetanilide sulfoxide was isolated from the exrcreta of germfree rats given oral doses of 2‐chloro‐ N ‐isopropylacetanilide. The metabolite was characterized by mass and nuclear magnetic resonance spectrometry on samples isolated from rats dosed with [1‐ 14 C]‐ and [2‐ 13 C]‐2‐chloro‐ N ‐isopropylacetanilide. Artifact formation upon reaction of the sulfoxide with alcoholic HCl is discussed.

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