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Field desorption mass spectrometry of basic peptides. An approach to the sequencing of arginine‐containing peptides
Author(s) -
Calas B.,
Méry J.,
Parello J.,
Promé J. C.,
Roussel J.,
Patouraux D.
Publication year - 1980
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200070705
Subject(s) - fragmentation (computing) , mass spectrometry , chemistry , arginine , peptide , desorption , ion , analytical chemistry (journal) , chromatography , amino acid , biochemistry , adsorption , organic chemistry , biology , ecology
Three basic hexapeptides which have two adjacent arginyl residues were studied by field desorption mass spectrometry. At low emitter temperature singly and doubly charged pseudomolecular ions [M + 1] + and [M + 2] 2+ were observed. At higher temperature, these peptides gave a relatively complex fragmentation pattern which can be explained as resulting from preferential cleavages involving the Arg‐Arg sequence. A mechanistic interpretation is proposed for this type of fragmentation.