Premium
An improved combined gas chromatographic mass spectrometric assay for the estimation of norphenazone in urine
Author(s) -
Murray S.
Publication year - 1980
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200070409
Subject(s) - chromatography , derivatization , urine , chemistry , gas chromatography , gas chromatography–mass spectrometry , mass spectrometry , chromatographic separation , high performance liquid chromatography , biochemistry
An improved, combined gas chromatographic mass spectrometric assay for the estimation of norphenazone in urine is described. A structural analogue of norphenazone is used as internal standard and derivatization of both norphenazone and the analogue gives these compounds better gas chromatographic properties. These modifications increase the precision and accuracy of the assay.