Premium
The identification of bile acid methyl esters by gas chromatography methane chemical ionization mass spectrometry
Author(s) -
Muschik Gary M.,
Wright Lynn H.,
Schroer James A.
Publication year - 1979
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200060608
Subject(s) - chemistry , chemical ionization , methane , mass spectrometry , chromatography , gas chromatography , methanol , gas chromatography–mass spectrometry , mass spectrum , bile acid , ion , ionization , organic chemistry , biochemistry
Methane chemical ionization mass spectrometric data and gas chromatography retention parameters are reported for 31 bile acid methyl esters. The group includes both saturated and unsaturated compounds with up to three keto or hydroxyl groups. Major ions include the quasimolecular ions and fragments resulting from the loss of neutral species such as methanol, water and methane. The combination of gas‐liquid chromatography retention and mass spectral data is sufficient for an unequivocal distinction among all the bile acids studied. Application of this data to the identification of bile acid metabolites is cited.