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[OH] − negative chemical ionization mass spectrometry. Reactions of [OH] − with methadone, l ‐α‐acetylmethadol and their metabolites
Author(s) -
Smit Andre L. C.,
Field F. H.
Publication year - 1978
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200051004
Subject(s) - chemical ionization , fragmentation (computing) , chemistry , ionization , methadone , mass spectrometry , mass spectrum , electron ionization , atmospheric pressure chemical ionization , analytical chemistry (journal) , chromatography , ion , organic chemistry , pharmacology , medicine , computer science , operating system
The [OH] − chemical ionization spectra of methadone and three metabolites and of l ‐α‐methadol and six metabolites are presented. The spectra are simple, but the methadol compounds exhibit much fragmentation. The ionization sensitivity is somewhat greater than that in CH 4 positive chemical ionization.