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Selected metastable peak monitoring: A new, specific technique in quantitative gas chromatography mass spectrometry
Author(s) -
Gaskell Simon J.,
Millington David S.
Publication year - 1978
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200050910
Subject(s) - mass spectrometry , chromatography , chemistry , analyser , gas chromatography , detection limit , fragmentation (computing) , analytical chemistry (journal) , gas chromatography–mass spectrometry , selected ion monitoring , ion mobility spectrometry , computer science , operating system
Using the combined electrostatic analyser‐magnet scan facility of a double focusing mass spectrometer, the daughter ion peak for the fragmentation, [M − 57] + → [M − 57–76] + , of a 5α‐dihydrotestosterone tert ‐butyldimethylsilyl ether was monitored during gas chromatography mass spectrometry. The detection limit was approximately 20 pg. The steroid was detected by this method in an extract of human blood plasma.