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Phenylacetic acid in human cerebrospinal fluid and plasma: Selected ion monitoring assay
Author(s) -
Fellows Linda E.,
King G. S.,
Pettit B. R.,
Goodwin B. L.,
Ruthven C. R. J.,
Sandler M.
Publication year - 1978
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200050809
Subject(s) - phenylacetic acid , cerebrospinal fluid , chromatography , chemistry , hydrolysis , human plasma , biochemistry , medicine , pathology
Phenylacetic acid has been detected in human cerebrospinal fluid and plasma. Free acid and total acid values obtained after hydrolysis have been quantified as the pentafluorobenzyl ester by selected ion monitoring, using [ 2 H 7 ]phenylacetic acid as internal standard.