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Mass spectrometry of N ‐methylsulfonylureas. A re‐examination
Author(s) -
Kossoy Aaron D.,
Occolowitz John L.
Publication year - 1978
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200050205
Subject(s) - lability , confusion , mass spectrum , mass spectrometry , electron ionization , chemistry , analytical chemistry (journal) , environmental chemistry , organic chemistry , chromatography , psychology , ion , psychoanalysis , ionization
Some confusion has arisen in the literature regarding the electron impact mass spectrum of N ‐methyltolbutamide. The situation is complicated by the thermal lability of this compound which causes the formation of the corresponding N ‐methylsulfonamide. We present here spectral data at relatively low probe temperatures (and without an intervening gas chromatographic system) which we believe define the mass spectrum of N ‐methyltolbutamide more accurately than before. Similar data are presented for the analogous N ‐methylacetohexamide and show a rearrangement process for both substances not reported previously for this class of compounds.