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Electron impact mass spectra of 1‐methyl‐oestra‐1,3,5(10)‐trienes having intact and 13,17‐ seco ‐D‐ring structures
Author(s) -
Vose Colin W.,
Coombs Maurice M.
Publication year - 1978
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200050116
Subject(s) - fragmentation (computing) , mass spectrum , electron ionization , ring (chemistry) , ion , oxime , chemistry , epoxide , spectral line , stereochemistry , medicinal chemistry , physics , organic chemistry , biology , catalysis , ecology , astronomy , ionization
Electron impact mass spectra of 1‐methyl‐oestra‐1,3,5(10)‐trien‐17‐one, its oxime, the homologous 18‐norketone, 1‐methyl‐oestra‐1,3,5(10),13(18)‐tetraene‐17‐carbonitrile and the corresponding 13,17‐ seco epoxide are described. The major fragmentation pathways of these compounds are reported and discussed in relation to their structures, and the structures of the ions m / e 144, 157, 170 and 183 characteristic of the 1‐methyl‐oestratriene skeleton are described. The relative abundances of these characteristic ions were shown to relate to the presence or absence of a 13,17‐ seco ‐D‐ring in these compounds.