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The mass spectra of 8‐azapurines
Author(s) -
Bose Samarendra N.,
Davies R. Jeremy H.,
Boyd Derek R.
Publication year - 1977
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200040506
Subject(s) - mass spectrum , fragmentation (computing) , metastability , polyatomic ion , ion , chemistry , electron ionization , spectral line , mass , deuterium , mass spectrometry , analytical chemistry (journal) , atomic physics , physics , organic chemistry , chromatography , astronomy , computer science , ionization , operating system
The mass spectra of 8‐azaadenine, 8‐azahypoxanthine, 2,6‐diamino‐8‐azapurine, 8‐azaxanthine and 8‐azaguanine are all characterized by intense molecular ion peaks. Fragmentation pathways are advanced to account for the other ions observed in the mass spectra and are supported by metastable transitions, accurate mass measurements and deuterium labelling studies. 8‐azaadenine and 8‐azahypoxanthine fragment initially by elimination of nitrogen from the molecular ion, but this is a minor process with the other compounds. In many respects the electron impact induced fragmentation of the 8‐azapurines is analogous to that of the corresponding purine derivatives.