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Gas chromatographic mass spectrometric computer analysis of volatile components in blood plasma from hemodialysis patients
Author(s) -
Dowty Betty,
Carlisle Douglas,
Laseter John L.,
Gonzalez Frank M.
Publication year - 1975
Publication title -
biomedical mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0306-042X
DOI - 10.1002/bms.1200020308
Subject(s) - chromatography , chemistry , mass spectrometry , hemodialysis , resolution (logic) , dialysis , plasma , capillary action , gas chromatography–mass spectrometry , adsorption , gas chromatography , analytical chemistry (journal) , organic chemistry , materials science , surgery , medicine , physics , quantum mechanics , artificial intelligence , computer science , composite material
Low molecular weight volatile organics extracted from the plasma of patients before and after hemodialysis were analyzed by high resolution capillary gas chomatographic mass spectrometric computer methods. The volatile components were collected on a polyphenyl ether solid adsorbent prior to analysis. Identification of components was achieved by mass spectrometry. Quantitaive changes were observed in both the plasma and dialysate composition with time. The method described provides a new means whereby the 100 or so low molecular weight organic volatiles of plasma can be monitored during the dialysis procedure.