Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton | Zendy

Uchiyama Seiichi | Zendy; Santa Tomofumi | Zendy; Okiyama Natsuko | Zendy; Fukushima Takeshi | Zendy; Imai Kazuhiro | Zendy

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Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Author(s) -

Uchiyama Seiichi,

Santa Tomofumi,

Okiyama Natsuko,

Fukushima Takeshi,

Imai Kazuhiro

Publication year - 2001

Publication title -

biomedical chromatography

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.4

H-Index - 65

eISSN - 1099-0801

pISSN - 0269-3879

DOI - 10.1002/bmc.75

Subject(s) - chemistry , reagent , fluorescence , chromatography , organic chemistry , quantum mechanics , physics

Fluorogenic and fluorescent labeling reagents having a benzofurazan (2,1,3‐benzoxadiazole) skeleton such as 4‐fluoro‐7‐nitro‐2,1,3‐benzoxadiazole (NBD‐F), 4‐ N,N ‐dimethylaminosulfonyl‐7‐fluoro‐2,1,3‐benzoxadiazole (DBD‐F), 4‐aminosulfonyl‐7‐fluoro‐2,1,3‐benzoxadiazole (ABD‐F), ammonium 7‐fluoro‐2,1,3‐benzoxadiazole‐4‐sulfonate (SBD‐F), 4‐hydrazino‐7‐nitro‐2,1,3‐benzoxadiazole (NBD‐H), 4‐ N,N ‐dimethylaminosulfonyl‐7‐hydrazino‐2,1,3‐benzoxadiazole (DBD‐H), 4‐nitro‐7‐ N ‐piperazino‐2,1,3‐benzoxadiazole (NBD‐PZ), 4‐ N,N ‐dimethylaminosulfonyl‐7‐ N ‐piperazino‐2,1,3‐benzoxadiazole (DBD‐PZ), 4‐( N ‐chloroformylmethyl‐ N ‐methyl)amino‐7‐ N,N ‐dimethylaminosulfonyl‐2,1,3‐benzoxadiazole (DBD‐COCl) and 7‐ N,N ‐dimethylaminosulfonyl‐4‐(2,1,3‐benzoxadiazolyl) isothiocyanate (DBD‐NCS) are reviewed in terms of synthetic method, reactivity, fluorescence characteristics, sensitivity and application to analytes. Copyright © 2001 John Wiley & Sons, Ltd.

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