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Reversed‐phase planar chromatography of some enantiomeric amino acids and oxazolidinones
Author(s) -
Lepri L.,
Boddi L.,
Bubba M. Del,
Cincinelli A.
Publication year - 2001
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.61
Subject(s) - cellulose triacetate , chemistry , enantiomer , chromatography , microcrystalline , bovine serum albumin , silica gel , microcrystalline cellulose , phase (matter) , enantiomeric excess , resolution (logic) , amino acid , organic chemistry , cellulose , enantioselective synthesis , crystallography , catalysis , biochemistry , artificial intelligence , computer science
The resolution of two enantiomeric amino acids and four structurally related oxazolidinones was evaluated by reversed‐phase planar chromatography using both home‐made microcrystalline cellulose triacetate (MCTA) layers and mobile phase additivies, such as β‐cyclodextrins (β‐Cy), modified α, β, γ cyclodextrins and bovine serum albumin (BSA), on commercially available RP‐18W/F 254 and SilC 18–50 /UV 254 plates. All the enantiomers were partially or baseline resolved by at least one of the chiral phases tested. Densitograms of optical antipodes and their mixtures were measured on MCTA layers developed with hydroalcoholic solvents. Copyright © 2001 John Wiley & Sons, Ltd.