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Introduction of the HPLC method for the determination of quinolone residues in various muscle tissues
Author(s) -
Kirbiš Andrej,
Marinšek Janez,
Flajs Vesna Cerkvenik
Publication year - 2005
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.435
Subject(s) - flumequine , enrofloxacin , chemistry , ciprofloxacin , residue (chemistry) , chromatography , muscle tissue , quinolone , danofloxacin , antibiotics , biochemistry , anatomy , biology
For use in veterinary sanitary control of foodstuffs and raw materials of animal origin in Slovenia, we developed a routine and confirmation analytical method for determining the residues of enrofloxacin, ciprofloxacin and flumequine in the muscle tissue of cattle, pigs and poultry. For the muscle tissue of freshwater fish, the determination of the flumequine residues was introduced. The results obtained through simultaneous determination of the residues of enrofloxacin, ciprofloxacin and flumequine showed that the values for the examined antibiotics were up to 600 times lower than the prescribed maximum residue levels (MRL). Another advantage of this method is that it covers a wide range of different fluoroquinolones. Copyright © 2005 John Wiley & Sons, Ltd.