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Chemiluminescence detection in HPLC and CE for pharmaceutical and biomedical analysis
Author(s) -
Li Famei,
Zhang Caihua,
Guo Xingjie,
Feng Wanyu
Publication year - 2003
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.238
Subject(s) - chemiluminescence , chemistry , derivatization , reagent , chromatography , high performance liquid chromatography , biochemical engineering , organic chemistry , engineering
The present paper reviews the developments and applications of chemiluminescence detection with HPLC and CE in pharmaceutical and biomedical analysis. The chemiluminescence systems, chemiluminogenic reagents and derivatization reagents, improvements in instrumental design as well as their contributions to the practical applications, are all presented. The advantages and limitations of current detection methodology and future prospects for improvement are briefly discussed. Copyright © 2003 John Wiley & Sons, Ltd.