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Resolution of enantiomers of amino acids by HPLC
Author(s) -
Bhushan R.,
Joshi Shalini
Publication year - 1993
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.1130070502
Subject(s) - enantiomer , chemistry , derivatization , reagent , resolution (logic) , chromatography , high performance liquid chromatography , amino acid , chiral stationary phase , chiral derivatizing agent , chiral column chromatography , organic chemistry , biochemistry , artificial intelligence , computer science
Application of HPLC as a prime tool in the area of enantiomeric resolution has opened doors of success and varied interest. Use of chiral reagents either indirectly (as derivatization reagent) or directly (added to stationary or mobile phase) has led to achieve resolution of a wide range of compounds. Amino acids, being important molecules with simple structure and easy availability, have been extensively studied. A bibliographic survey on HPLC resolution of amino acids and derivatives along with a brief discussion on general methods of enantiomeric separation has been presented.