Premium
Plasma concentrations of β‐carotene, vitamin A and vitamin E after β‐carotene and vitamin E intake
Author(s) -
Postaire E.,
Kouyate D.,
Rousset G.,
Regnault C.,
Lati E.,
Bejot M.,
Gossioux P.,
Hazebroucq G.
Publication year - 1993
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.1130070306
Subject(s) - carotene , chemistry , vitamin , chromatography , beta carotene , vitamin e , food science , biochemistry , antioxidant
We have studied the metabolism (absorption) of β‐carotene and vitamin E by assigning eleven volunteers to receive daily two capsules of OENOBIOL, each containing 15 mg of β‐carotene and 15 mg of vitamin E, over 60 days. The β‐carotene, vitamin E and vitamin A plasma levels were then determined using new methods developed in our laboratory. After two months, the actively treated group's median β‐carotene and vitamin E levels were significantly higher than those of a control group. However, no significant change between treated and control groups in the mean of vitamin A (retinol) plasma levels were observed. Treatment with β‐carotene, a vitamin A precursor, does not significantly modify the vitamin A levels. This conclusion had already been observed and it is assumed that a plasma level of β‐carotene equal or higher than 0.3 mg/L reflects a nutritional intake of provitamins sufficient to support homeostasis of retinol (Brubacher et al ., 1982).