Premium
The measurement of nucleoside deaminases by high performance liquid chromatography and their use in clinical chemistry
Author(s) -
Sherwood R. A.
Publication year - 1991
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.1130050602
Subject(s) - cytidine deaminase , adenosine deaminase , chemistry , guanosine , cytidine , nucleoside , chromatography , enzyme , adenosine , amp deaminase , adenosine deaminase deficiency , biochemistry
The measurement of the nucleoside deaminases—cytidine deaminase, guanosine deaminase and adenosine deaminase—by reversed phase high performance liquid chromatography is reviewed. The clinical value of assaying the enzyme activity is discussed for each of these enzymes. Both cytidine deaminase and adenosine deaminase measurements have proven clinical value, although the use of the assay of cytidine deaminase in the diagnosis of pre‐eclampsia is probably not helpful.