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Automated quantitative microcolumn chromatography of haemoglobin A 2
Author(s) -
Ersser R. S.,
Blight Leonie,
Hjelm N. M.,
Chambers K.,
James D.
Publication year - 1991
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.1130050510
Subject(s) - chemistry , chromatography , densitometry , elution , quantitative analysis (chemistry) , ion chromatography , quantum mechanics , physics
Abstract Automated cation exchange microcolumn chromatography of haemoglobins has been modified for the analysis of haemoglobin A 2 . It provides the quantitative data of sufficient precision and specificity for the investigation of potential heterozygotes for β‐thalassaemia. Results have been compared with an established method of electrophoresis followed by densitometry of the eluted bands.