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Identification of peroxyacetic acid uroporphyrin I in the urine of patients with congenital erythropoietic porphyria by liquid chromatography and mass spectrometry
Author(s) -
Guo Rong,
Rideout J. M.,
Chai W.,
Lawson A. M.,
Lim C. K.
Publication year - 1991
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.1130050202
Subject(s) - chemistry , porphyrin , chromatography , urine , mass spectrometry , porphyria , high performance liquid chromatography , liquid chromatography–mass spectrometry , biochemistry , medicine
A new porphyrin, peroxyacetic acid uroporphyrin I, has been isolated from the urine of patients with congenital erythropoietic porphyria by reversed phase high performance liquid chromatography. The porphyrin was characterized by high resolution mass spectrometry and by typical chemical reactions of a peroxyacid.