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Isolation and characterization of β‐hydroxypropionic acid‐ and hydroxyacetic acid‐uroporphyrin I in the urine of a patient with congenital erythropoietic porphyria by high performance liquid chromatography and liquid secondary ion mass spectrometry
Author(s) -
Guo Rong,
Chaim W.,
Rideout J. M.,
Lawson A. M.,
Lim C. K.
Publication year - 1990
Publication title -
biomedical chromatography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.4
H-Index - 65
eISSN - 1099-0801
pISSN - 0269-3879
DOI - 10.1002/bmc.1130040404
Subject(s) - chemistry , chromatography , urine , mass spectrometry , high performance liquid chromatography , biochemistry
β‐Hydroxypropionic acid‐ and hydroxyacetic acid‐uroporphyrin I have been isolated from the urine of a patient with congenital erythropoietic porphyria by reversed phase high performance liquid chromatography. The compounds were characterized by their chemical behaviour and confirmed by liquid secondary ion mass spectrometry.