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Introductory bioinformatics exercises utilizing hemoglobin and chymotrypsin to reinforce the protein sequence‐structure–function relationship
Author(s) -
Inlow Jennifer K.,
Miller Paige,
Pittman Bethany
Publication year - 2007
Publication title -
biochemistry and molecular biology education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 39
eISSN - 1539-3429
pISSN - 1470-8175
DOI - 10.1002/bmb.30
Subject(s) - sequence (biology) , function (biology) , chymotrypsin , computer science , bioinformatics , hemoglobin , computational biology , biology , biochemistry , genetics , trypsin , enzyme
We describe two bioinformatics exercises intended for use in a computer laboratory setting in an upper‐level undergraduate biochemistry course. To introduce students to bioinformatics, the exercises incorporate several commonly used bioinformatics tools, including BLAST, that are freely available online. The exercises build upon the students' background knowledge of hemoglobin and chymotrypsin, and foster a better understanding of how protein sequence relates to structure and function.