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Development of the enzyme–substrate interactions concept inventory
Author(s) -
Bretz Stacey Lowery,
Linenberger Kimberly J.
Publication year - 2012
Publication title -
biochemistry and molecular biology education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 39
eISSN - 1539-3429
pISSN - 1470-8175
DOI - 10.1002/bmb.20622
Subject(s) - substrate (aquarium) , reliability (semiconductor) , function (biology) , curriculum , enzyme , psychology , quality (philosophy) , biochemistry , chemistry , pedagogy , biology , epistemology , microbiology and biotechnology , philosophy , ecology , power (physics) , physics , quantum mechanics
Enzyme function is central to student understanding of multiple topics within the biochemistry curriculum. In particular, students must understand how enzymes and substrates interact with one another. This manuscript describes the development of a 15‐item Enzyme–Substrate Interactions Concept Inventory (ESICI) that measures student understanding of enzyme–substrate interactions. The validity and reliability of ESICI data were established through multiple methods. Results from the administration of the ESICI to biochemistry students across the United States ( N = 707) are discussed in terms of instrument quality. The manuscript concludes with suggestions for how to use the ESICI for both teaching and biochemistry education research.