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Teaching glycoproteins with a classical paper: Knowledge and methods in the course of an exciting discovery
Author(s) -
Zhu Lixin
Publication year - 2008
Publication title -
biochemistry and molecular biology education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 39
eISSN - 1539-3429
pISSN - 1470-8175
DOI - 10.1002/bmb.20224
Subject(s) - glycoprotein , protein subunit , atpase , scientific thinking , chemistry , computer science , biochemistry , computational biology , mathematics education , psychology , biology , enzyme , gene
To integrate research into the teaching of glycoproteins, the story of discovering hydrogen‐potassium ATPase (HK‐ATPase) β subunit is presented in a way covering all the important teaching points. The interaction between the HK‐ATPase α subunit and a glycoprotein of 60–80 kDa was demonstrated to support the existence of the β subunit. On revealing the strategies and experimental designs of this discovery, the knowledge of glycoproteins is delivered. The purpose of this effort was to facilitate the teaching of scientific thinking in the science classroom, to make the biochemistry classroom a more interesting place, and to attract uncertain minds into the career of biochemistry research.