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Oxidatively Induced Reductive Elimination for Methyl Group Transfer via Isolable Transmetalation Complexes
Author(s) -
Kim Jinwoo,
Jin Seongho,
Kim Dongwook,
Chang Sukbok
Publication year - 2021
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.12235
Subject(s) - reductive elimination , transmetalation , metallacycle , chemistry , iridium , ruthenium , photochemistry , oxidative addition , medicinal chemistry , combinatorial chemistry , stereochemistry , catalysis , organic chemistry , x ray crystallography , physics , diffraction , optics
Herein, we describe the mechanistic details on the oxidatively induced reductive elimination of isolated methyl iridium and ruthenium metallacycle complexes. It was demonstrated that the otherwise challenging C─C bond formation is indeed facilitated by external oxidation, being enabled under mild conditions. Computational analyses supported the proposed high‐valent pathway, where the energy barrier for reductive elimination significantly decreases upon the metallic oxidation to facilitate the desired C─C bond formation.