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Pd‐Catalyzed Asymmetric Synthesis of 3, 4‐Dihydroisoquinolinones From N ‐Ts‐Benzamides and 1, 3‐Dienes
Author(s) -
Kim Tae Kyun,
Youn So Won
Publication year - 2021
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.12227
Subject(s) - chemistry , annulation , catalysis , ligand (biochemistry) , stereochemistry , combinatorial chemistry , stereoselectivity , pyridine , oxazoline , medicinal chemistry , organic chemistry , receptor , biochemistry
A Pd(II)‐catalyzed asymmetric oxidative annulation of N ‐Ts‐benzamides with 1,3‐dienes using a chiral pyridine‐oxazoline‐type ligand for the regio‐ and stereoselective synthesis of chiral 3,4‐dihydroisoquinolinones has been developed.