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Visible‐Light Photoredox‐Catalyzed α‐Allylation of α‐Bromocarbonyl Compounds Using Allyltrimethylsilane
Author(s) -
Gontala Arjun,
Jang Gwang Seok,
Woo Sang Kook
Publication year - 2021
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.12219
Subject(s) - reagent , chemistry , yield (engineering) , catalysis , functional group , organic chemistry , carbonyl group , combinatorial chemistry , reaction conditions , photochemistry , medicinal chemistry , metallurgy , materials science , polymer
The development of a greener allylation reagent for α‐allylation of carbonyl compounds is of great necessity. Here we present allyltrimethylsilane as a novel allylation reagent in the photoredox‐catalyzed α‐allylation of carbonyl compounds such as ketones, esters, and amides. The reaction process shows good functional group tolerance and generates a good yield of the product. The reaction mechanism is a radical‐mediated reaction by photo‐induced single electron transfer.