Premium
In( III )‐Catalyzed O ‐Annulation of Cyclic Diazodicarbonyls with 2‐Naphthol , 6‐Quinolinol , β‐Tetralone , and 9‐Phenanthrol to Access Diverse Benzochromones
Author(s) -
Maezono Shizuka Mei Bautista,
Khanal Hari Datta,
Chaudhary Priyanka,
Park Ga Eul,
Lee Yong Rok
Publication year - 2021
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.12207
Subject(s) - chemistry , ketene , annulation , tetralone , catalysis , intramolecular force , domino , carbene , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry
In(III)‐Catalyzed O ‐annulation of cyclic diazodicarbonyl compounds with 2‐naphthols, 6‐quinolinol, β‐tetralone, and 9‐phenanthrol is developed. This novel synthetic strategy paves a facile and desired access to diverse and functionalized benzochromones. This imperative protocol involves domino carbene generation, ketene formation through Wolff‐rearrangement, nucleophilic addition, H‐migration, intramolecular cyclization, and elimination of water.