Premium
Identification of TRE‐130 as Reversible Inhibitor of Pan‐EGFR Mutants while Sparing EGFR Wild‐Type Activity
Author(s) -
Duggirala Krishna Babu,
Choe Hyeonjeong,
Jeon Byeong Uk,
Jung Myoung Eun,
Go Areum,
Lim Byungho,
Park Chaewon,
Yoon Jiyeun,
Chae Chong Hak,
Cho Byoung Chul,
Choi Gildon,
Lee Kwangho
Publication year - 2019
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.11886
Subject(s) - cyan , mutant , identification (biology) , wild type , type (biology) , computational biology , chemistry , cancer research , computer science , microbiology and biotechnology , biology , biochemistry , gene , botany , physics , ecology , optics
Proposed binding mode of TRE‐130 (thick cyan sticks) in the EGFR.