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Chiral Resolution of Racemic 2‐Pyrone Diels‐Alder Cycloadduct by Diastereomeric Salt Formation
Author(s) -
Jeon TaeHong,
Kang HyungJoon,
Svirid Anastasia,
Lyakhov Alexander,
Kovalenko Vitaly,
Cho CheonGyu
Publication year - 2019
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.11838
Subject(s) - diastereomer , chemistry , cinchonidine , salt (chemistry) , cycloaddition , diels–alder reaction , resolution (logic) , quinidine , stereochemistry , organic chemistry , enantioselective synthesis , catalysis , artificial intelligence , computer science , medicine , pharmacology
An efficient protocol was developed that allows resolution of racemic bicyclolactone carboxylic acid obtained from the Diels‐Alder cycloaddition of 3,5‐dibromo‐2‐pyrone by formation of diastereomeric salts with quinidine and cinchonidine.