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1 H‐NMR ‐based Metabolomic Study of Miamiensis avidus ‐infected Olive Flounder
Author(s) -
Yoon Dahye,
Yoon Changshin,
Choi Hyeonsoo,
Noh Hyeonkyung,
Ok Youngjun,
Kim DoHyung,
Kim HeuiSoo,
Kim Suhkmann
Publication year - 2017
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.11150
Subject(s) - paralichthys , metabolomics , olive flounder , anaerobic exercise , hypoxia (environmental) , nuclear magnetic resonance spectroscopy , flounder , biology , chemistry , medicine , microbiology and biotechnology , fish <actinopterygii> , physiology , bioinformatics , fishery , stereochemistry , oxygen , organic chemistry
The scuticociliate Miamiensis avidus ( M. avidus ) is an aetiological agent of mass mortalities in cultured fish worldwide. The external signs of infection by this histiophagous parasite are hemorrhage, muscle ulceration, and exophthalmia. In this study, we infected olive flounder ( Paralichthys olivaceus ) with M. avidus under laboratory conditions, and used 1 H ‐nuclear magnetic resonance ( NMR ) spectroscopy to detect the metabolomic alterations during the infection. Multivariate data analysis showed that there were distinct differences in metabolomes between the control and the infected groups. Analysis of the metabolomic changes indicated that the olive flounder experienced severe metabolic shifts to anaerobic respiration and hypoxia.