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A New Rhodamine B‐based Fluorescent Probe for pH Detection and Bioimaging under Strong Acidic Conditions
Author(s) -
Yang Quan,
Zou Jingrong,
Chirumarry Sridhar,
Huo Chang,
Tang Linlin,
Zhang Fang,
Xiang Yi,
Zuo Hua,
Shin DongSoo,
Peng Xiang
Publication year - 2016
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.10888
Subject(s) - fluorescence , rhodamine , chemistry , rhodamine b , photochemistry , metal , hydrazine (antidepressant) , nuclear chemistry , combinatorial chemistry , chromatography , organic chemistry , catalysis , physics , photocatalysis , quantum mechanics
A new pH ‐sensitive rhodamine derivative was designed and synthesized using coupling reaction of rhodamine hydrazine with commercially available 3‐bromo‐4‐hydroxybenzaldehyde, and characterized via NMR , HRMS , UV and fluorescent spectra. The obtained probe was marked with yellow fluorescence under neutral condition and pink in strongly acidic media. It has high quantum yields, is not susceptible to metal interference, and has high penetration ability for cell membrane and also further applicable in bioimaging.