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Solid‐phase Total Synthesis of Amide Analogues of Coibamide A: Azacoibamide A and O ‐Desmethyl Azacoibamide A
Author(s) -
Sable Ganesh A.,
Park Jaekwan,
Lim SooJeong,
Lim Dongyeol
Publication year - 2016
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.10674
Subject(s) - desmethyl , amide , chemistry , solid phase synthesis , methylation , combinatorial chemistry , total synthesis , stereochemistry , phase (matter) , cancer cell lines , organic chemistry , peptide , cancer cell , biochemistry , metabolite , dna , cancer , medicine
The azacoibamide A and O‐desmethyl azacoibamide A: amide analogues of natural coibamide A were synthesized via a solid‐phase peptide synthesis. The synthetic samples were analyzed by 2D NMR techniques for structural studies.