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Flavones from the Bark of Lindera caudata and Their Anti‐Tobacco Mosaic Virus Activity
Author(s) -
Yang YuChun,
Qin Ying,
Wu XianXue,
Xia CongFang,
Meng YanLin,
Zhou Bin,
Ye YanQing,
Gao XueMei,
Li YinKe,
Hu QiuFen
Publication year - 2015
Publication title -
bulletin of the korean chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.237
H-Index - 59
ISSN - 1229-5949
DOI - 10.1002/bkcs.10216
Subject(s) - flavones , tobacco mosaic virus , chemistry , hydroxymethyl , bark (sound) , mosaic virus , flavonoid , stereochemistry , botany , virus , biology , organic chemistry , plant virus , virology , chromatography , ecology , antioxidant
Two new flavones, 5‐hydroxy‐8‐hydroxymethyl‐7,4′‐dimethoxy‐flavone ( 1 ) and 6‐hydroxy‐8‐hydroxymethyl‐7,4′‐dimethoxy‐flavone ( 2 ), together with six known flavones ( 3–8 ), were isolated from the bark of Lindera caudata . The structures of 1–8 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1–8 were evaluated for their anti‐tobacco mosaic virus (anti‐ TMV ) activity. The results showed that Compounds 1 and 2 showed high anti‐ TMV activity with inhibition rates of 31.2 and 28.8%, respectively. These values are close to those of positive control.
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