Open AccessRandomized clinical trial of remote ischaemic preconditioning versus no preconditioning in the prevention of perioperative myocardial infarction during open surgery for ruptured abdominal aortic aneurysm
Author(s) -
Pedersen T. F.,
BudtzLilly J.,
Petersen C. N.,
Hyldgaard J.,
Schmidt J.O.,
Kroijer R.,
Grønholdt M.L.,
Eldrup N.
Publication year - 2018
Publication title -
bjs open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.974
H-Index - 9
ISSN - 2474-9842
DOI - 10.1002/bjs5.55
Subject(s) - medicine , perioperative , myocardial infarction , abdominal aortic aneurysm , ischemic preconditioning , randomized controlled trial , surgery , odds ratio , acute kidney injury , anesthesia , abdominal surgery , vascular surgery , aneurysm , cardiology , ischemia , cardiac surgery
Remote ischaemic preconditioning (RIPC) has been suggested as a means of protecting vital organs from reperfusion injury during major vascular surgery. This study was designed to determine whether RIPC could reduce the incidence of perioperative myocardial infarction (MI) during open surgery for ruptured abdominal aortic aneurysm (AAA). Secondary aims were to see if RIPC could reduce 30-day mortality, multiple organ failure, acute intestinal ischaemia, acute kidney injury and ischaemic stroke.