Open AccessAbstracts of the 6th Annual Scientific Meeting of the British Obesity & Metabolic Surgery Society (BOMSS), 22–23 January 2015, Newcastle Gosforth Park Marriott Hotel
Author(s) -
Akhila Mallipedhi,
Thinzar Min,
Sarah L. Prior,
G. Dunsheath,
Richard M. Bracken,
Jonathan Barry,
Scott Caplin,
Nia Eyre,
James S. Morgan,
John Baxter,
Saoirse E. O'Sullivan,
Sarir Sarmad,
David A. Barrett,
Stephen C. Bain,
Steve Luzio,
Jeffrey W. Stephens
Publication year - 2015
Publication title -
british journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.202
H-Index - 201
eISSN - 1365-2168
pISSN - 0007-1323
DOI - 10.1002/bjs.9794
Subject(s) - medicine , general surgery , gerontology , obesity surgery , obesity , family medicine , gastric bypass , weight loss
Reductions in plasma endocannabinoids following bariatric surgery in morbidly obese females with impaired glucose homeostasis: A non-randomized prospective study • Endocannabinoids (ECs) are bioactive lipid mediators − N-arachidonyl ethanolamine (AEA) − N-palmitoyl ethanolamine (PEA) − N-oleoyl ethanolamine (OEA) − related N-acylethanolamine (NAE) derivatives − 2-arachidonyl glycerol (2-AG) • Endocannabinoid system (ECS) plays a critical role in regulation of body weight and may have a role in aetiopathogenesis of Type 2 Diabetes (T2DM) • Elevated circulating levels of AEA and 2-AG in obese people compared to non-obese controls of both genders • Little information available on the effects of extreme weight loss associated with bariatric surgery in relation to the ECS.